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The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

https://doi.org/10.1016/j.jbc.2022.102089

Murphy, Robert D.; Chen, Tiantian; Lin, Jianping; He, Rongjun; Wu, Li; Pearson, Caden R.; Sharma, Savita; Vander Kooi, Carl D.; Sinai, Anthony P.; Zhang, Zhong-Yin; et al (July 2022, Journal of Biological Chemistry)

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Generation and characterization of a laforin nanobody inhibitor

https://doi.org/10.1016/j.clinbiochem.2021.03.017

Simmons, Zoe R.; Sharma, Savita; Wayne, Jeremiah; Li, Sheng; Vander Kooi, Craig W.; Gentry, Matthew S. (July 2021, Clinical Biochemistry)

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Oligomerization and carbohydrate binding of glucan phosphatases

https://doi.org/10.1016/j.ab.2018.10.003

Sharma, Savita; Vander Kooi, Carl D.; Gentry, Matthew S.; Vander Kooi, Craig W. (December 2018, Analytical Biochemistry)

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Cooperative Kinetics of the Glucan Phosphatase Starch Excess4

https://doi.org/10.1021/acs.biochem.1c00307

Mak, Claudia A.; Weis, Kenyon; Henao, Tiffany; Kuchtova, Andrea; Chen, Tiantian; Sharma, Savita; Meekins, David A.; Thalmann, Matthias; Vander Kooi, Craig W.; Raththagala, Madushi (July 2021, Biochemistry)

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